VMIH-associated publications

VMIH-associated contributors are underlined.

JOURNAL ARTICLE: Chen MZ, Yuen D, McLeod VM, Yong KW, Smyth CH, Rossi Herling B, Payne TJ, Fabb SA, Belousoff MJ, Algarni A, Sexton PM, Porter PJH, Pouton CW, Johnston APR. A Versatile Antibody Capture System that Drives Precise In Vivo Delivery of mRNA loaded Lipid Nanoparticles and Enhances Gene Expression. Nat. Nanotech. 2025. https://www.nature.com/articles/s41565-025-01954-9

JOURNAL ARTICLE: Uckelmann M, Levina V, Taveneau C, Ng XH, Pandey V, Martinez J, Mendiratta S, Houx J, Boudes M, Venugopal H, Trépout S, Fulcher AJ, Zhang Q, Flanigan S, Li M, Sierecki E, Gambin Y, Das PP, Bell O, de Marco A, Davidovich C. Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates. Nat Struct Mol Biol. 2025 Mar, 32(3):520-530. doi: 10.1038/s41594-024-01457-6. Epub 2025 Jan 15. PMID: 39815045

JOURNAL ARTICLE: Cevaal PM, Kan S, Fisher BM, Moso MA, Tan A, Liu H, Ali A, Tanaka K, Shepherd RA, Kim Y, Ong J, Furtado DL, Holz M, Purcell DFJ, Casan JML, Payne T, Zhao W, Fareh M, McMahon JH, Deeks SG, Hoh R, Telwatte S, Pouton CW, Johnston APR, Caruso F, Symons J, Lewin SR, Roche M. Efficient mRNA delivery to resting T cells to reverse HIV latency. Nat Commun. 2025 May 29, 16(1):4979. doi: 10.1038/s41467-025-60001-2.PMID: 40442114

JOURNAL ARTICLE: Liu H, Chen MZ, Payne T, Porter CJ, Pouton CW, Johnston AP. Beyond the Endosomal Bottleneck: Understanding the Efficiency of mRNA/LNP Delivery. Adv. Funct. Mater. 2024, 2404510. https://doi.org/10.1002/adfm.202404510

JOURNAL ARTICLE: Chen MZ, Yuen D, McLeod VM, Yong KW, Smyth CH, Rossi Herling B, Payne TJ, Fabb SA, Belousoff MJ, Algarni A, Sexton PM, Porter PJH, Pouton CW, Johnston APR. A Versatile Antibody Capture System that Drives Precise In Vivo Delivery of mRNA loaded Lipid Nanoparticles and Enhances Gene Expression. Nat. Nanotech. 2025. https://www.nature.com/articles/s41565-025-01954-9

JOURNAL ARTICLE: Chen J, Cortez-Jugo C, Kim C-J, Lin Z, Wang T, De Rose R, Xu W, Wang Z, Gu Y, Caruso F. Metal-Phenolic-Mediated Assembly of Functional Small Molecules into Nanoparticles: Assembly and Bioapplications. Angew. Chem. Int. Ed. 2024, 63, e202319583.Angew. Chem. Int. Ed. 2024, 63, e202319583. https://doi.org/10.1002/anie.202319583

JOURNAL ARTICLE: Gail EH, Healy E, Flanigan SH, Jones N, Ng XH, Uckelmann M, Levina V, Zhang Q, Davidovich C. Inseparable RNA binding and chromatin modification activities of a nucleosome-interacting surface in EZH2. Nature Genetics. 2024 DOI:10.1038/s41588-024-01740-8.

JOURNAL ARTICLE: Al-Wassiti HA, Fabb SA, Grimley SL, Kochappan R, Ho JK, Wong CY, Tan CW, Payne TJ, Takanashi A, Lee CL, Mugan RS, Sicilia H, Teo SLY, McAuley J, Ellenberg P, Cooney JP, Davidson KC, Bowen R, Pellegrini M, Rockman S, Godfrey DI, Nolan TM, Wang LF, Deliyannis G, Purcell DFJ, Pouton CW. mRNA vaccines encoding membrane-anchored RBDs of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting. Mol Ther Methods Clin Dev. 2024 Nov 15, 32(4):101380. doi: 10.1016/j.omtm.2024.101380. eCollection 2024 Dec 12.PMID: 39687732

JOURNAL ARTICLE: Takanashi A, Pouton CW*, and Al-Wassiti H*. Delivery and Expression of mRNA in the Secondary Lymphoid Organs Drive Immune Responses to Lipid Nanoparticle-mRNA Vaccines after Intramuscular Injection. Mol. Pharmaceutics 2023, 20, 8, 3876–3885.

JOURNAL ARTICLE: Ohtomo H, Ito S, McKenzie NJ, Uckelmann M, Wakamori M, Ehara H, Furukawa A, Tsunaka Y, Shibata M, Sekine S-I, Umehara T, Davidovich C, Koseki H, Nishimura Y. H2A Ubiquitination Alters H3-tail Dynamics on Linker-DNA to Enhance H3K27 Methylation. J Mol Biol. 2023 435(4):167936.

JOURNAL ARTICLE: Nolan TM, Deliyannis G, Griffith M, Braat S, Allen LF, Audsley J, Chung AW, Ciula M, Gherardin NA, Giles ML, Gordon TP, Grimley SL, Horng L, Jackson DC, Juno JA, Kedzierska K, Kent SJ, Lewin SR, Littlejohn M, McQuilten HA, Mordant FL, Nguyen THO, Soo VP, Price B, Purcell DFJ, Ramanathan P, Redmond SJ, Rockman S, Ruan Z, Sasadeusz J, Simpson JA, Subbarao K, Fabb SA, Payne TJ, Takanashi A, Tan CW, Torresi J, Wang JJ, Wang LF, Al-Wassiti H, Wong CY, Zaloumis S, Pouton CW, Godfrey DI. Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster. EBioMedicine. 2023 Dec;98:104878. doi: 10.1016/j.ebiom.2023.104878. Epub 2023 Nov 27. PMID: 38016322; PMCID: PMC10696466.

JOURNAL ARTICLE: Healy E, Zhang Q, Gail EH, Agius SC, Sun G, Bullen M, Pandey C, Das PP, Polo JM, Davidovich C. The apparent loss of PRC2 chromatin occupancy as an artifact of RNA depletion. Cell reports 2024, 43 (3). https://doi.org/10.1016/j.celrep.2024.113858

JOURNAL ARTICLE: McCoullough LC, Fareh M, Hu W, Sozzi V, Makhlouf C, Droungas Y, Lee CL, Takawy M, Fabb SA, Payne TJ, Pouton CW, Netter HJ, Lewin SR, Purcell DF, Holmes JA, Trapani JA, Littlejohn M, Revill PA. CRISPR-Cas13b-mediated suppression of HBV replication and protein expression. J Hepatol. 2024 Nov;81(5):794-805. doi: 10.1016/j.jhep.2024.05.025. Epub 2024 May 28.

JOURNAL ARTICLE: Gu Y, Chen J, Wang Z, Liu C, Wang T, Kim C.-J, Durikova H, Fernandes S, Johnson DN, De Rose R, Cortez-Jugo C, Caruso F. mRNA Delivery Enabled by Metal–Organic Nanoparticles. Nat. Commun. 2024, 15, 9664 https://doi.org/10.1038/s41467-024-53969-w

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2024

2023